John P. A. Ioannidis

John P. A. Ioannidis (born 1965 in New York City) is a professor and chairman at the Department of Hygiene and Epidemiology, University of Ioannina School of Medicine as well as tenured adjunct professor at Tufts University School of Medicine and Professor of Medicine and Director of the Stanford Prevention Research Center at Stanford University School of Medicine.[1][2]

Biography

He was born in 1965 and raised in Athens, Greece. He graduated first in his class at the University of Athens Medical School, then attended Harvard University for his medical residency in internal medicine. He then did a fellowship at Tufts University for infectious disease.[3]

Ioannidis' 2005 paper Why Most Published Research Findings Are False[4] has been the most downloaded technical paper from the journal PLoS Medicine.[5] As the link shows, this paper has met much approval, though Goodman and Greenland criticized it in a short comment[6] and a longer analysis.[7] Ioannidis has answered this critique.[8]

A profile of his work in this area appears in the Nov 2010 issue of The Atlantic.[9] The Atlantic article notes Ioannidis analyzed "49 of the most highly regarded research findings in medicine over the previous 13 years". And "Of the 49 articles, 45 claimed to have uncovered effective interventions. Thirty-four of these claims had been retested, and 14 of these, or 41 percent, had been convincingly shown to be wrong or significantly exaggerated."[10]

References

  1. ^ "John P. A. Ioannidis". Department of Hygiene and Epidemiology, University of Ioannina School of Medicine. http://users.uoi.gr/hyepilab/people.php. Retrieved 2008-12-31. 
  2. ^ Ioannidis, John P.A.. "Curriculum Vitae". http://www.dhe.med.uoi.gr/data/cv/CV102010D.pdf. Retrieved 4 November 2010. 
  3. ^ David H. Freedman (2010). Wrong: Why Experts Keep Failing Us. Little, Brown and Company. ISBN 0316023787. http://books.google.com/books?id=XS4TQgAACAAJ&dq. "Born in 1965 in the United States to parents who were both physicians, he was raised in Athens, where he showed unusual aptitude in mathematics and snagged Greece's top student math prize. ..." 
  4. ^ Ioannidis, J. P. A. (2005). "Why Most Published Research Findings Are False". PLoS Medicine 2 (8): e124. doi:10.1371/journal.pmed.0020124. PMC 1182327. PMID 16060722. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1182327.  edit
  5. ^ Robert Lee Hotz (2007-09-14). "Most Science Studies Appear to Be Tainted By Sloppy Analysis". Science Journal WSJ.com (Dow Jones & Company). http://online.wsj.com/public/article_print/SB118972683557627104.html. 
  6. ^ Goodman, S.; Greenland, S. (2007). "Why Most Published Research Findings Are False: Problems in the Analysis". PLoS Medicine 4 (4): e168. doi:10.1371/journal.pmed.0040168. PMC 1855693. PMID 17456002. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1855693.  edit
  7. ^ Steven Goodman and Sander Greenland (2007). "Assessing the unreliability of the medical literature: A response to "Why most published research findings are false"". Johns Hopkins University, Department of Biostatistics. http://www.bepress.com/jhubiostat/paper135. 
  8. ^ Ioannidis, J. P. A. (2007). "Why Most Published Research Findings Are False: Author's Reply to Goodman and Greenland". PLoS Medicine 4 (6): e215. doi:10.1371/journal.pmed.0040215. PMC 1896210. PMID 17593900. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1896210.  edit
  9. ^ David H. Freedman (Nov 2010) Lies, Damned Lies, and Medical Science, The Atlantic
  10. ^ Ioannidis, J. P. A. (2005). "Contradicted and Initially Stronger Effects in Highly Cited Clinical Research". JAMA: the Journal of the American Medical Association 294 (2): 218–228. doi:10.1001/jama.294.2.218. PMID 16014596.  edit

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